Forlle’d scientists introduced new approach to sustain mineral balance beside cellular bio-stimulation and maintaining proper extracellular environment.

Despite the immense achievements in mineral science, great breakthroughs still to be expected, especially in relation to their effect on the formation of tissues and organs, activation of enzymes and chemical reactions, as well as their impact on the development of various diseases.

In medicine and cell biology it is well known the importance of certain minerals and their impact on cell behavior, for example calcium play an important role in attaching suprabasal layers of the epidermis to the basal layer, copper activate peptides that control cell renewal and healing process, Zinc as part of dependent enzymes in insulin hormones, Iodine for thyroid hormone, Iron as part of hemoglobin, Selenium, Platinum and gold as antioxidants as well as major minerals such as Calcium, Sodium, Chloride, Magnesium, Phosphorus and Potassium which control nerve impulses, muscle contractility, transport across cell membranes etc.

For proper physiological activity living organisms must have a controlled balance between cation and anion. If this balance is disturbed serious side effects may result. If we take for example, the four life-support minerals: sodium, potassium, calcium and magnesium, sodium ion shares the cell outside while potassium ion shares the cell inside and the cell is working resiliently between those two elements. Calcium and magnesium are supposed to exist in and outside the cell and maintain mineral balance.

Food mass production and use of pesticides as well as artificial fertilizers, has lead to over usage of the soil and its depletion from minerals, which is the main reason living organisms aren’t receiving sufficient amount of minerals in their diet. Considering the fact that living organisms can’t synthesize or produce these inorganic solid substances, providing these minerals to the body and in our case the skin is of great importance.

It is not an exaggeration to say that imbalance or deficiency in minerals may contribute to most if not all health complications, for example moisture contained in the human body and other living forms such as plants, insects and microorganisms resemble a good conductor for electrical impulses that are responsible for the transformation of energy and activation of biological active reactions. In order for water to be a good conductor it requires minerals, bearing in mind that pure water without mineral ions is a bad conductor.

In cosmetic industry it is common to use minerals with one valence such as sodium and potassium that are water soluble, easily absorbed by the skin and enhance the solubility of other active ingredients, however in order to maintain mineral balance it is important to introduce another minerals with +2 valence such as calcium and magnesium which have bad solubility in water.

In order to supply skin cells with calcium and magnesium as sodium and potassium it is important to ionize these elements and introduce them as part of an organic acid because organic acid can decompose into sodium bi-carbonate which act as a buffer in an acidic/basic solution and produce carbonate gas and water as end products through the trichloroacetic acid cycle. Water produced can increase the moisture level in the skin without causing any stress on the organism.

Inorganic acids in comparison to organic acids remain an anion and most of inorganic acids form precipitates or crystals upon reaction with calcium which has bad reflection on the solubility and the organism in general. In addition to its physiological value, the anhydride compound of calcium discharge ions such as phosphorus, nitrogen and chloride that remain in the body and require additional cation to neutralize them, thus maintaining balance between cation and anion for proper physiological function.

To introduce minerals as part of organic compounds such as, calcium acetate, calcium malate, calcium gluconate, etc. fermentation process is applied using different types of yeast, enzymes, lactic acid bacteria etc. Low molecular hyaluronic acid (5 nm) in Forlle’d products beside its major role as moisturizer and stabilizer of the extracellular matrix; it transports calcium and magnesium to the skin. The ability of low molecular hyaluronic acid to transport ions with two valence such as Ca+2 has been demonstrated in different studies such as transporting calcium to spermatozoids with low motility to increase their activity.

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Advantages of Ionized Minerals in Forlle’d products